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It helps switch on the brain-to-hormone pathway that controls GnRH, which then
The second hit involves progressive hepatic injury, contributing to conditions such as steatohepatitis, advanced fibrosis, and cirrhosis [20]
In such systems, the ascorbateglutathione cycle, together with TRXs, PRXs, glutaredoxins (GRXs), and antioxidant enzymes, such as superoxide dismutase (SOD) and catalase (CAT), ensures appropriate redox-mediated regulation, so that ROS, ascorbate, and glutathione can accumulate in the required compartment-specific manner
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