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Osteoarthritis is also biologically heterogeneous, involving cartilage, bone, synovium, nerves, and systemic metabolic factors rather than a single disease pathway. Mandelbaum said there are lifestyle factors people can adopt to help lower the risk of osteoarthritis as well as its painful effects

Lower Blood Pressure : Weight loss can reduce hypertension, and lower the chances of cardiovascular diseases

Some individuals also experience modest improvements in their blood sugar levels, especially if using semaglutide for diabetes management

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