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Prevailing models propose that plant vacuolar sorting receptors (VSRs) recycle either from multivesicular bodies (MVBs) to the trans-Golgi network (TGN) or from the TGN to the Golgi apparatus and/or endoplasmic reticulum (ER)

Furthermore, neutrophils from lupus-prone mice or Systemic Lupus Erythematosus (SLE) patients undergo ferroptosis, which leads to the disruption of immune tolerance in SLE

This process is part of the inflammatory cascade and a big issue with people suffering from auto-immune or chronic fatigue-related conditions

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