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Query haplotypes classified with discordant shortest-distance and average-distance subtyping or with bootstrap scores below 70 were tagged as doubtful
To date, only a single, methodologically limited, placebo-controlled trial has evaluated its effects on maximal physical performance in healthy athletes, and its results actually point toward negative trends in both physical and mental performance ( Consequently, Meldonium's international reputation as a powerful performance enhancer appears to be built primarily on anecdotal use, theoretical biochemical mechanisms, and the inappropriate extrapolation of data from compromised animal models and ischemic patients
S4J, Supplementary Fig
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