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showed appendectomy was associated with a lower risk of CC (HR = 0.90, 95% CI = 0.810.99) and distal CC (HR = 0.77, 95% CI = 0.650.90) ( Several limitations to this study deserve our attention: First, this study mainly included GWAS summary data of Europeans, and the results may not be extended to other ethnic groups

that rapid weight loss may affect bone density, especially in populations already vulnerable to bone loss

MPG is a synthetic aminothiol antioxidant that is used in the treatment of cystinuria, rheumatoid arthritis, liver and skin disorders 34

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