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Creadore, A

3D culture models with CRISPR screens reveal hyperactive NRF2 as a prerequisite for spheroid formation via regulation of proliferation and ferroptosis

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The most commonly reported adverse effects are gastrointestinal disturbances , including: Nausea and stomach discomfort Diarrhoea or loose stools Loss of appetite Mild abdominal pain or bloating These symptoms are typically mild and often resolve with continued use or by taking CoQ10 with food, which can also enhance absorption