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As the primary factors for the reduced anticancer effect 1) the reduced delivery and uptake of the anticancer agent, 2) the need for the conversion of molecular oxygen (O 2 ) into reactive oxygen species (ROS), 3) the preferred therapeutic effect against highly proliferating cells, which is reduced under hypoxic conditions, or 4) adaptation of the cancer cells by promoting cell survival and upregulating certain resistance pathways, has been suggested 1,2,3,4,5
The neurologic side effects include confusion, dizziness, drowsiness, slurred speech, balancing issue, loss of consciousness, muscular paralysis, fatigue, numbness, tingling, and/or burning
Semaglutide begins affecting appetite within the first weeks, but visible weight loss builds gradually
Consult and work closely with your healthcare provider for this specific concern
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