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Still, larger studies, including patients from other parts of the world and a longer treatment period, are needed to validate methylcobalamins therapeutic effects in this subset of ALS patients, the authors noted.

Other considerations Headache and dizziness may occur, particularly during initial treatment

More methionine is needed to deactivate estrogens when estrogen levels are elevated to prevent the increased estrogens from reducing the flushing of fat from the liver and increasing cholesterol levels

Despite its growing popularity among athletes and its wide availability through non-regulated sources, there is minimal human data available