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Disrupted gut microbiota may lead to increased intestinal permeability (leaky gut), molecular mimicry (e.g., cross-reactivity between bacterial antigens and TPO), and activation of Th17/IL-17 pathways
93) with increased risks of cirrhosis, hepatocellular carcinoma (liver cancer), and cardiovascular disease (94)
The AWARD-7 trial, which is notable for its exclusive focus on patients with moderate-to-severe chronic kidney disease, demonstrated that dulaglutide users, particularly those simultaneously using ACE inhibitors or angiotensin receptor blockers, exhibited a substantially less eGFR decline compared to insulin glargine users
Only high grade NAC promotes whole body skin lightening effect
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