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The highest parasite burden in the CNS is observed around 7 dpi when schistosomula are localized mostly in the thoracic and cervical spinal cord [40, 41]

Ischemia modified albumin (IMA) is calculated by binding cobalt to albumin

To address the critical issue of BBB permeability, studies using [H]Dihexa and [C]inulin in rats revealed that Dihexa avidly concentrated in all examined brain regions including the prefrontal cortex, hippocampus, hypothalamus, striatum, thalamus, midbrain, brain stem, and cerebellum, compared to blood

In preclinical models, NNMT inhibition has been shown to mimic and boost exercise-mediated improvements in muscle function, even in sedentary subjects