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Ethics declarations Competing interests J.J.N

Contribution statement MA contributed to the generation of the results and analysis using the TriNetX platform and took the lead on writing the manuscript

For some, however, these symptoms might be persistent enough to affect their quality of life, leading to what's humorously termed a "Hangover." Serious side effects can include pancreatitis and kidney problems, which require immediate medical attentionthink "Stat!" In terms of safety, Semaglutide bears a boxed warning for thyroid C-cell tumors, a red flag for at-risk patients

This dual dependency on CYP3A4 and P-gp creates a well-defined vulnerability