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PAs beneficial effects might be attributed to iron chelation, decreased CYP2E1 mRNA expression, increased SIRT -1 expression at both mRNA and protein levels, and decreasing oxidative stress

To follow up on this indication that patients with schizophrenia exhibit physiological differences in T cell responses, Craddock and colleagues undertook a more systematic investigation of T cell proliferative responses by conducting a microarray analysis of differentially expressed genes in isolated T cells from schizophrenia patients and controls

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