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Chidester, who frequently uses radiofrequency-based Renuvion in body-contouring surgery, says that, in his experience, it does work in certain areas, on select GLP-1 patients, with one exception: Stretch-marked skin does not do well with any of these energy devicesit just doesn't tighten. And in GLP-1 patients, were seeing so many stretch marks, says Ashley Gordon, MD, a board-certified plastic surgeon in Austin

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Sample preparation (B) In an alternate protocol, the frozen liver tissue was directly lysed by probe sonication (2 10 pulse, 40% power output) in 4 M urea/DPBS and briefly cleared of debris by centrifugation (5000 g , 5 min, 4 C)