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Furthermore, children with IGF-1 deficiency-primary GH insensitivity or children with Laron syndrome who were treated with biosynthetic IGF-1 (165) showed increases in their serum alkaline phosphatase and serum procollagen and IGF-binding protein-3 (IGFBP-3) (165167)

Angiogenesis (Blood Vessel Formation): It promotes the formation of new blood vessels by stimulating VEGF (vascular endothelial growth factor), enhancing wound healing

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Oral doses up to 2000 mcg a day may be needed to get enough vitamin B12 in the blood