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This process may initiate the inappropriate incorporation of selenocysteine (SeCys) and selenomethionine (SeMet) into proteins, as well as impair their function, which may in turn lead to the development of oxidative stress, i.e., a state in which the oxidizing potential increases to the level that threatens the stability of cellular structures [14]

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The systematic name of this enzyme class is S-(hydroxymethyl)glutathione:NAD + oxidoreductase

The response to oxidative stress in the model is surprisingly complex