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Enzyme treatments, such as transglutaminase (TG) and tyrosinase, have been explored for their ability to reduce the allergenicity of TM by altering its structure and reducing its IgE-inducing capacity

But if you are asking what is likely, the briefing docs are the strongest signal we have

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Im waiting for a call back from my GP so Im going to ask for a test for my folate levels, and a renal screen if they dont suggest it