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The process used to detoxify cyanocobalamin could deplete glutathione reserves, a compound necessary for this detoxification

In normal physiology it participates in hepatic fat processing and methylation reactions, and it contributes to the livers handling of triglycerides and cholesterol

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A recent study performed in a population of cats clinically diagnosed as hyperthyroid, without other diseases, did not report the presence of hypocobalaminemia [80]