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Moreover, as understanding of GLP-1 biology expands, researchers are also investigating its effects on the gut-brain axis

Cells undergoing ferroptosis release damage-associated molecular patterns (DAMPs), including high mobility group box 1 (HMGB1), ATP, and oxidized lipid species, which serve as potent triggers for inflammatory responses [157,158,159]

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Advice for Healthcare Professionals The MHRA has advised that healthcare professionals remain vigilant for symptoms of acute pancreatitis, which may be challenging to recognise in early stages, and use GLP-1/GIP receptor agonists and GLP-1RAs with caution in patients with a history of pancreatitis