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The provoked or unprovoked nature of deep vein thrombosis, as well as the chronicity of any provoking risk factors (transient or persistent), has significant prognostic and treatment implications, as recurrence risk and anticoagulation regimens differ accordingly.141 Deep vein thrombosis requires anticoagulation with unfractionated heparin, fondaparinux, low molecular weight heparins, direct oral anticoagulants, or vitamin K antagonists

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Currently, treatment of insomnia in T2DM primarily involves symptomatic therapies, including relief of pain, adherence to good sleep hygiene, and use of hypnotics such as benzodiazepine receptor agonists and zolpidem