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These injectable therapies, often administered once weekly, provide sustained, controlled release, ensuring steady therapeutic effects with minimal intervention

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In a SAXENDA clinical trial in adult patients with overweight (excess weight) or obesity with type 2 diabetes mellitus treated with basal insulin and SAXENDA in combination with a reduced-calorie diet and increased physical activity and up to 2 oral anti-diabetes medications, severe hypoglycemia was reported by 3 (1.5%) of 195 SAXENDA-treated patients and 2 (1%) of 197 placebo-treated patients

Yet, receptors for glutamate are found on a variety of immune cells, including lymphocytes and dendritic cells, suggesting that glutamate has a role in immune cell functioning (176)