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Studies using the Broad Institute's Connectivity Map found that GHK significantly increased expression of DNA repair genes with 47 genes stimulated and 5 genes suppressed, providing a mechanism for cellular recovery from various forms of damage

Collagen IV is a basement membrane collagen critical for organized skin and tissue architecture following wound repair

It also affects the same person differently on different occasions

Additionally, the FOXO4-p53 interaction contributes to the maintenance of senescent cells by activating the transcription of their common target gene, p21cip1, which suppresses apoptosis 36