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The broader picture is that the next generation of obesity treatments involves multi-target approaches, whether through single molecules activating multiple receptors (tirzepatide, retatrutide, survodutide, mazdutide) or through combination therapies pairing separate compounds (CagriSema)

A control group of about 300 patients took SGLT-2 inhibitors (e.g., canagliflozin, dapagliflozin, empagliflozin), drugs that are comparable to GLP-1 receptor agonists at lowering blood glucose levels