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Medical Criteria for Case Eligibility Gastroparesis, literally meaning stomach paralysis, is a chronic neuromuscular disorder characterized by delayed gastric emptying without evidence of mechanical obstruction, where the stomachs normal coordinated muscle contractions (peristalsis) become impaired or cease functioning entirely

Most clinical guidance supports treatment for at least 12 months, with ongoing therapy recommended for patients who respond well and have no significant side effects

Moreover, sc semaglutide showed neuroprotective activity in a stroke animal model, improved motor control and muscle strength, and reduced infarct volume, loss of neurons, and inflammation [66]