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Nitric oxide is also believed to play a major role in the smooth muscle relaxation of sexual arousal.14 Additionally, the increase in blood circulation from nitric oxides vasodilation properties can reduce vaginal dryness, as vaginal lubrication is actually ultra-filtered blood.19 L-Citrulline L-Citrulline is partially converted to L-arginine, which is then converted to nitric oxide, meaning that this amino acid can also promote NO production.10 Research on L-citrulline for sexual dysfunction usually involves it being used with L-arginine, and most of the research on L-citrulline alone involves men