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No significant effects on androgen or estrogen receptor systems have been reported, which is relevant context for distinguishing BPC-157 from anabolic compounds that do carry such risks

While many patients have had safe treatment using oral selenium as monotherapy at 100200 mcg per day and long-term intakes from food and supplements of approximately 800 mcg per day are rated as safe, it is important to exclude selenium as a contributing factor to type 2 hyperthyroidism due to ingestion of high dietary selenium levels, for example, from overuse of sports nutrition supplements

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Different varieties of herbal suppositories have been used for hundreds of years to address both vaginal and rectal complaints (Romm, 2010)