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While the immediate gastrointestinal side effects of semaglutide are a concern, experts also consider the long-term benefits of improved glycemic control and weight reduction, which can positively impact overall health and potentially reduce acid reflux symptoms in the long run

For patients with type 2 diabetes, the American Diabetes Association recommends checking HbA1c every three months until glycemic targets are achieved, then at least twice yearly thereafter

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The brief also draws on previous FDA precedent - such as its non-enforcement stance on Makena in 2011 - to show that cost and access concerns have historically shaped drug policy decisions