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GLP-1s approved for weight loss show dramatic results: In clinical trials, once-a-week Wegovy (semaglutide) for 68 weeks led to an average weight loss of 14.9% from baseline body weight, while 86.4% of all participants taking Wegovy saw clinically significant weight lossgenerally defined as losing 5% or more of baseline body weight during the trial

(3) Y Asadi, R K Moundounga, A Chakroborty, A Pokokiri, and H Wang (2025) FOXOs and their roles in acute and chronic neurological disorders Frontiers in Molecular Bioscience

GLP-1 weight loss drugs are changing how people shop GLP-1 use isn't just drastically changing the lives of those who are on the weight-loss drugs