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Key Takeaways Start with 12.5 mg daily and adjust based on testosterone levels and symptom response Most men achieve therapeutic testosterone levels within 8-12 weeks of treatment Regular lab monitoring every 6-8 weeks optimizes dosing and safety Preserve fertility and natural testosterone production compared to direct hormone replacement Dosing adjustments should be made gradually with at least 4-week intervals between changes Starting Enclomiphene Dosing Protocol The standard starting dose for enclomiphene is 12.5 mg taken orally once daily, preferably at the same time each day

Wahidin Sudirohusodo Hospital in Makassar, and the Universitas Sumatera Utara Teaching Hospital in Medan

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