Quantitative PCR was performed to quantify the expression levels of the tested genes
[DOI] [PubMed] [Google Scholar] 99.Picillo M, Pivonello R, Santangelo G, Pivonello C, Savastano R, Auriemma R, Amboni M, Scannapieco S, Pierro A, Colao A, Barone P, and Pellecchia MT
Pharmacophore modeling is a powerful tool for drug discovery, but its effectiveness heavily relies on the availability of both active molecules and the biological target ( 3.6 Experimental validation After applying the virtual screening protocol (Supplementary Figures S2), we identified 18 candidate molecules based on their docking scores and MMGBSA free energy calculations
It provides intensified fat metabolism support which may suit active individuals, athletes and those with higher training volumes