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Men may experience more pronounced abdominal and visceral fat reduction, while women may notice improvements in both truncal and lower body fat depending on receptor distribution and individual physiology

It triggers a clean GH pulse with minimal effect on cortisol or prolactin

The cautious approach for women in their 50s with a family history of hormone-sensitive cancers is to discuss the question with both the prescribing clinician and the womans oncologist or primary care provider before initiating any peptide that elevates IGF-1

Agerelated declines of 13 % per year in GH, melatonin, and cortisol further underscore the need for targeted interventions