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On the other hand, this model suggests we should not use immune checkpoint inhibitors to boost immune responses

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TGF-1 is one of core targets of PF, playing a positive role in the development of idiopathic pulmonary fibrosis (IPF) through many signaling pathways, such as Smad, MAPK, and ERK (Ye and Hu, 2021)

Zhao Y, Truhlar DG (2008) The M06 suite of density functionals for main group thermochemistry, thermochemical kinetics, noncovalent interactions, excited states, and transition elements: two new functionals and systematic testing of four M06-class functionals and 12 other functionals