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In the first case, this is due to the fact that NEM does not react with GSH under acidic conditions

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This research peptide is commonly evaluated in studies involving copper peptide pathway research, skin matrix pathway models, collagen pathway research, extracellular matrix behavior, peptide-metal complex signaling, matrix remodeling models, and controlled cellular response mechanisms

Some studies have also investigated the peptides relationship with growth factor signaling and inflammatory mediators that participate in tissue remodeling