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Chien KS, Borthakur G, Naqvi K, Daver NG, Montalban-Bravo G, Cortes JE, DiNardo CD, Jabbour E, Alvarado Y, Andreeff M , Bose P, Jain N, Sheppard K, Klingner-Winton C, Pierce SA, Dong XQ, Soltysiak KA, Kantarjian HM, Garcia-Manero G

It is characterized by ROS-induced dissociation of the oxygen-sensitive kinase KEAP1, activating the NRF2 signaling pathway and caspase-8-dependent cell death [241, 242]

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