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CHMP approval recommendations in the European Union are running at 44 as of late November 2025, contrasting sharply with the European Medicines Agencys revitalised performance in 2024, which saw the CHMP (Committee for Medicinal Products for Human Use) recommend 64 new drugs for approval, compared with 50 in 2023

A review of the molecular pathways mediating the improvement in diabetes mellitus following caloric restriction

11 Effectively reducing NTBI uptake mediated by DMT1 has been shown to reduce iron-induced damage, suggesting that DMT1 may be a promising target for alleviation of ferroptosis

doi: 10.1073/pnas.0400181101