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Patients should always rely on local regulations and physician guidance

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Patients with these risk factors should discuss screening and supplementation strategies with their GP, particularly if experiencing symptoms such as fatigue, paraesthesia, glossitis, or cognitive changes suggestive of deficiency

doi: 10.3389/fnut.2025.1739173 Received 04 November 2025 Revised 04 December 2025 Accepted 15 December 2025 Published 02 April 2026 Volume 12 - 2025 Edited by Eric Gumpricht, Independent Researcher, Gilbert, AZ, United States Reviewed by Etore Signini, Federal University of So Carlos, Brazil Lara Russo, National Research Council (CNR), Italy Updates Copyright 2026 Lin, Zhang, Pu and Peng