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SFN activates the antioxidant and anti-inflammatory responses by inducing Nrf2 pathway and inhibiting NF-B

And a third pathway, one that has become central to autoimmune research, generates regulatory T cells, also called Tregs

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KEY TAKEAWAYS Low sperm count (oligospermia) means fewer than 16 million sperm per mL of semen (WHO 6th edition), and it contributes to roughly half of all infertility cases Common causes include varicocele, hormonal imbalances, oxidative stress, lifestyle factors, and environmental exposures A semen analysis is the primary diagnostic test, but hormone panels and genetic screening may also be needed Antioxidant supplements including CoQ10, zinc, selenium, and L-carnitine have shown measurable improvements in sperm concentration and motility in clinical trials Sperm take approximately 72-90 days to develop, so most natural interventions require at least 3 months to show results Lifestyle changes, diet, exercise, sleep, stress management, and reducing heat exposure, form the foundation of any natural treatment plan What Causes Low Sperm Count