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Dysregulation will persist to enhance autoreactive T cell activation and lead to disease progression and exacerbation ( Changes in the gut microbiota can significantly impact the production of short-chain fatty acids (SCFAs) and other metabolites which in turn modulate systemic inflammation and immunity

Immortalized BMDMs were maintained in RPMI 1640 with 2 mM L-glutamine, 1 penicillinstreptomycin (GenClone), 10% (v/v) heat-inactivated FBS (R&D Systems) and 20% conditioned medium

Glutathione + GAP technology (glutathione amino acid precursors) work to minimise irritation while amping up antioxidant protection and ingredient stability

Cercarial pellets were resuspended and washed thrice in serum-free M199 medium and collected at 100 g for 5 min