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As direct incorporation of acrylamide into MRTX849 without a linker ( DJX-A-KF ) resulted in only moderate degradation under the same conditions, thus the exellent degradation efficacy of DJX-A-KM appears dependent on the spatial arrangement of the acrylamide group relative to the prolinol moiety

According to the results of animal studies, the abnormalities found in electrophysiological tests may precede the structural changes in the retina and optic nerve observed in fundus examination or imaging tests (Eells et al.1996

Has anyone else had this with lupus? While researchers dont know if lupus can directly cause low vitamin B12 also known as a vitamin B12 deficiency some medications and conditions associated with lupus may make it more likely