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10.1111/j.1468-3083.2010.03803.x 27 SauzetO.CarvajalA.EscuderoA.MolokhiaM.CorneliusV

Overview Obesity, defined by the World Health Organization as any Body Mass Index value equal to or greater than 30, is one of the worlds most common chronic medical conditions and a risk factor for several of the worlds most common causes of premature death: heart disease, stroke, diabetes, and certain cancers

CYP24A1, a gene that provides instructions for making the enzyme 24-hydroxylase, is involved in the catabolism of both 25(OH)VD 3 and 1,25(OH) 2 D 3, thereby limiting vitamin D receptor (VDR)/1,25(OH) 2 D 3 signaling 14

Importance of physical exercise