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Roberts BR, Ryan TM, Bush AI, Masters CL, Duce JA

Best Melasma Treatments in 2025: What Dermatologists Recommend Overview of Proven Treatment Categories Top dermatologists combine various modalities for optimal results: Topical depigmenting agents In-clinic dermatological procedures Oral therapies and supplements Lifestyle and UV protection measures Why Combination Therapy Is Often More Effective Melasma is multifactorial and requires a layered approach

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doi: 10.1152/ajpgi.1992.263.5.G617