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The modern diet, which typically contains up to 15 times more omega-6 PUFAs than omega-3 PUFAs, along with a common deficiency of DHA in the brain, results in the production of large amounts of lipid mediators derived from LA and AA, contributing to chronic inflammation and oxidative stress implicated in cardiovascular, metabolic, inflammatory, and neuropsychiatric disorders (18, 50, 5759)

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These structural differences between SLU-PP-332 and 5-amino-1mq translate into distinct pharmacological properties, which we will explore in the following sections