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Folate should be supplemented with it, particularly to help prevent colorectal cancer, which this drug otherwise promotes (Patel 2009

GHK-Cu's copper component can cause irritation in sensitive individuals

RT-qPCR analyses validated the upregulation of ATF4 target genes, including SLC1A1, SLC7A8 , phosphoserine aminotransferase 1 ( PSAT1 ), and serine hydroxymethyltransferase 2 ( SHMT2 ) in T315I-Bcr-Abl cells (Fig