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This effect is not mere scavenging
G protein-coupled receptor 40 (GPR40) The orthosteric partial GPR40 agonist TAK-875 (fasiglifam) resulted in glucose improvement in T2D patients (131) but the development was halted in Phase III due to potential liver toxicity (132)
AQP4 is the primary water channel in astrocytes, densely localized at perivascular end feet and critical for maintaining brain water homeostasis
Preserved incretin activity of glucagon-like peptide 1[7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
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