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This is most commonly attributed to weight loss and reduced body fat insulation rather than a direct pharmacological effect

It's consistency over time

A much higher proportion of participants preferred the dulaglutide device (84.2%) compared with the semaglutide device (12.3%)

However, several factors can affect its effectiveness: Dosing variations: Without standardized manufacturing, actual drug content may vary Stability concerns: Custom formulations might not remain stable as long as FDA-approved versions Injection technique: Different formulations may require different injection methods Storage requirements: Compounded versions might have different temperature or light sensitivity Safety Considerations Common Side Effects Both Ozempic and compounded semaglutide can cause similar side effects since they contain the same active ingredient