how to tell if glutathione is working Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation Glutathione: Uses, Dosage, Side Effects

Mol Biol Rep 51 , 729 (2024)

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Glutamate excitotoxicity can lead to increased production of neuronal nitrogen oxide synthase (nNOS) which in turn can lead to higher production of reactive nitrogen species, damage to cellular components, and ultimately, cell death (Sullivan and Brown, 2005), and this is thought to be mediated by the oxidative stress triggered by excitotoxicity (Nguyen et al., 2011)