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UB251, on which Novo is partnered with United Biotechnology, targets the receptors for GLP-1, GIP and glucagon

With advancements in microbiome research, gut microbiota have been identified as pivotal regulators of host metabolism and immunity, modulating host redox homeostasis through metabolite secretion, epithelial barrier repair, and immunomodulation [6,7,8]

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Dual GIP/GLP-1 receptor agonists, such as tirzepatide, are promising molecules that not only improve glycemic control but also reduce body weight