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Less urgent but still worth reporting: side effects that do not improve after seven days at any dose level, persistent diarrhea that interferes with daily activities, significant hair thinning (which can occur during rapid weight loss phases and may relate to nutritional deficiencies rather than medication directly), mood changes including increased anxiety or depression, and hair loss patterns that seem disproportionate to weight loss speed

It is not typically used for people with type 1 diabetes or those with a history of severe gastrointestinal issues, such as gastroparesis

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