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Published studies have reported enhanced angiogenesis, reduced inflammatory marker expression, and accelerated wound closure in preclinical models

Patients should disclose a history of pancreatitis, gallbladder disease, severe gastrointestinal disease, kidney disease or dehydration risk, use of diabetes medications such as insulin or sulfonylureas, pregnancy or plans for pregnancy, and any personal or family history of medullary thyroid carcinoma or MEN2

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In these conditions, the gut lining is compromised, allowing endotoxins and other antigens to leak into the bloodstream and trigger an immune response