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But here's the really scary part - acetaldehyde is a known carcinogen

As most lipids in the brain are contained in the membrane phospholipids, the main outcome of lipid peroxidation is the structural damage of membranes, causing structural changes that impact membrane fluidity and permeability, neurotransmission, signaling, ion transport, and impaired electrical conduction

Therefore, higher proinsulin levels in the thymus are hypothesized to induce negative selection of insulin-specific thymocytes, thereby increasing tolerance to insulin autoantigens ( INS locus in central tolerance and demonstrate that genetic variants can impact both disease risk and progression, underscoring the need to investigate other non-HLA genes associated with T1D

Jonathan Picker, Fragile X Program Director, and was updated by Dr