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Description

Crosstalk between the gut and brain in ischemic stroke: mechanistic insights and therapeutic options

It is not appropriate for everyone, which is why conditions such as liver, kidney, or cardiac disease and pregnancy are screened first

In light of the connection between wtIDH1 activity and glutamine metabolism, we tested the activity of a small molecule glutaminase inhibitor, CB-839, and observed increased sensitivity to the drug in IDH1/ cells (Extended Data Fig